Chronic osteomyelitis is a severe and persistent condition that engages bone and bone marrow. The infection can be limited to the bone, or it can propagate to the bone marrow, the periosteum, and the surrounding soft tissues. It represents a major financial every health system and impacts the quality of life of the affected patients. Diagnosing chronic osteomyelitis remains difficult. Accordingly, laboratory and imaging studies are necessary in this respect. A 49-year-old man after high energy trauma underwent debridmant and fixation. After 3 years’ patient admitted in infection ward with fever presentation. The clinical examination didn't reveal any sign of localization of fever. Chronic osteomyelitis is not always associated with fever in this situation Other diagnoses should be considered after role out other disease osteomyelitis

Keywords: chronic osteomyelitis, Hodgkin lymphoma, left tibia fibula

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