Volume 3, Issue 1 (2-2016)                   J. Res. Orthop. Sci. 2016, 3(1): 0-0 | Back to browse issues page


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1- Department of Orthopedics, Trauma and Hand Surgery, St. Marien Hospital, Siegen, Germany
Abstract:   (1151 Views)
Introduction: Alkaptonuria (AKU) is a very rare disease and occurs due to the deficiency of the enzyme homogentisate1, 2-dioxygenase (HGD) which results in ochronosis, a term used to describe the dark pigmentation of the tissues. Alkaptonuria affects mostly the knee joint followed by the hip as major weight bearing joints, where the life quality of such patients is severely affected.
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Subject: Knee surgery
Received: 2019/09/9 | Accepted: 2016/02/15 | Published: 2016/02/15

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