Volume 9, Issue 3 (8-2022)
JROS 2022, 9(3): 157-164 |
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Ebrahimpour A, Biglari F, Sabaghzadeh A, Barazandeh Rad S, Sadighi M, Moradian T et al . Comparing the Effects of Vitamins C and D in Preventing Complex Regional Pain Syndrome After Distal Radius Fracture Treatment. JROS 2022; 9 (3) :157-164
URL: http://jros.iums.ac.ir/article-1-2221-en.html
URL: http://jros.iums.ac.ir/article-1-2221-en.html
Adel Ebrahimpour1 
, Farsad Biglari1 , Amir Sabaghzadeh1 , Saber Barazandeh Rad1 , Mehrdad Sadighi1 , Tohid Moradian1 , Meisam Jafari Kafiabadi 1
, Farsad Biglari1 , Amir Sabaghzadeh1 , Saber Barazandeh Rad1 , Mehrdad Sadighi1 , Tohid Moradian1 , Meisam Jafari Kafiabadi 1
1- Department of Orthopedic Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract: (251 Views)
Background: The inflammatory response following trauma is the possible pathophysiology of complex regional pain syndrome (CRPS) I, caused by the release of pro-inflammatory factors and neuropeptides. Vitamins C and D are two antioxidants that can effectively prevent the occurrence of CRPS I.
Objectives: The primary aim of this study was to compare the effectiveness of vitamins C and D in preventing the occurrence of CRPS following the fixation of distal radius fractures.
Methods: The study was performed from January 1, 2018 to the end of December 2019. Patients who had fractured distal radius were candidates for external fixation and PCP. The patients were divided into three groups: 1) Receiving 500 mg of vitamin C daily for 50 days, 2) Receiving an oral dose of vitamin D of 5000 IU weekly for 50 days, and 3) Receiving no complementary medicine (control group).
Results: Of the 150 fractures, 62 type C3, 56 type C2, and 32 type C1 were observed, constituting 41.3%, 37.3%, and 21.3% of the total. During the two follow-up sessions, CRPS occurred in 28 patients (18.7%). Among the 28 patients mentioned, 14 patients (50%) belonged to group C, 8 patients (28.6%) belonged to group B, and 6 patients (21.4%) belonged to group A.
Conclusion: The use of vitamins C and D reduced the incidence of CRPS in patients with distal radius fractures. Also, the use of these vitamins was significantly effective in improving CRPS and reducing pain and ROM limitation.
Objectives: The primary aim of this study was to compare the effectiveness of vitamins C and D in preventing the occurrence of CRPS following the fixation of distal radius fractures.
Methods: The study was performed from January 1, 2018 to the end of December 2019. Patients who had fractured distal radius were candidates for external fixation and PCP. The patients were divided into three groups: 1) Receiving 500 mg of vitamin C daily for 50 days, 2) Receiving an oral dose of vitamin D of 5000 IU weekly for 50 days, and 3) Receiving no complementary medicine (control group).
Results: Of the 150 fractures, 62 type C3, 56 type C2, and 32 type C1 were observed, constituting 41.3%, 37.3%, and 21.3% of the total. During the two follow-up sessions, CRPS occurred in 28 patients (18.7%). Among the 28 patients mentioned, 14 patients (50%) belonged to group C, 8 patients (28.6%) belonged to group B, and 6 patients (21.4%) belonged to group A.
Conclusion: The use of vitamins C and D reduced the incidence of CRPS in patients with distal radius fractures. Also, the use of these vitamins was significantly effective in improving CRPS and reducing pain and ROM limitation.
Type of Study: Research Article |
Subject:
Trauma
Received: 2022/02/12 | Accepted: 2022/03/28 | Published: 2022/08/1
Received: 2022/02/12 | Accepted: 2022/03/28 | Published: 2022/08/1
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