• Online Submission
This journal accepts only manuscripts through the online submission system. It is easy to use and easy to track, thus by conducting all steps electronically, your submission will be expedient. Contributors can submit via our website. Once you submit an article, it will be forwarded to one of the editors and afterwards to at least two peer-reviewers. The author will be notified of the submission process by means of E-mail.
 
• Required Fields for Submission
The following items are necessary for submission:

 
• Cover Letter
This letter should be uploaded online as a word file. The corresponding author should briefly explain the aim of the current study and should state that the manuscript has not been and will not be published or submitted elsewhere during the process of review and after in case of acceptance. The financial disclosure should be declared. The letter must include a statement declaring that the study complies with current ethical considerations. Authors reporting experimental studies on human subjects must include a statement of assurance in the Materials and Methods section of the manuscript reading that: (1) informed consent was obtained from each patient included in the study and (2) the study protocol conforms to the ethical guidelines of the 1975 Declaration of Helsinki. The authors should also disclose all conflict of interests in the cover letter. If there is no conflict of interest, please state “the authors declare no conflict of interest”. Authors should declare in the cover letter that all figures of their manuscripts are original.
 
• Title Page
The title page should state:
- Title: Capitalize the initial of each word except prepositions with less than three letters.
- Author(s) information: Full name, Email and phone number (optional) of all authors should be mentioned.
- Affiliation: Author’s affiliation containing Department, University, City, and Country should be mentioned precisely.
- Corresponding author: One of the authors should be chosen as the corresponding author. Address, telephone and fax number, and E-mail of the corresponding author should be written in the title page. ORCID ID of corresponding and first authors is necessary for submission.
- Conflict of interest statement: All sources of potential conflicts of interest (financial or non-financial) should be disclosed. If no conflict exists, declare “the authors have no conflict of interest to disclose”.
- Compliance with ethical guideline: A statement confirming that the study was approved by the appropriate institutional and/or national research ethics committee.
- Funding: Information regarding whether and by whom the research was supported.
- Authors' contributions: To promote transparency, all the contributions such as conception and design, data collection and analysis, drafting the manuscript, etc, should be specified. In the end, it should be noted that “All authors read and approved the final manuscript”.
- Acknowledgment: This section provides opportunity to thank those who have helped but do not have the authorship criteria. If none, state so.
- Type of article: This journal publishes research articles, systematic review articles, meta-analyses, review articles, case reports, letter to editors and brief reports.
 
• Research Articles
Structured abstract (maximum 250 words) in the following subheadings: Background, Objectives, Materials/Patients and Methods, Results, and Conclusion. Original article should contain up to 3500 words (allowed reference count is 50, allowed illustrations/tables & figures is 8).

• Research Article Body
Generally includes the: Background, Objectives, Materials/Patients and Methods, Results, Discussion, Conclusion, and References.
- Background: This should summarize the rationale for the study.
- Objectives: State the aims of the study.
- Materials/Patients and Methods: This should include exact method or observation or experiment. If an apparatus is used, its manufacturer’s name and address should be given in parentheses. If a drug is used, its generic name, dose, and route of administration must be given. Statistical method must be mentioned and specify any general computer program used.
- Results: Must be presented in the form of text, tables and illustrations.The contents of the tables should not be all repeated in the text. Instead, a reference to the table number may be given. Long articles may need sub-headings within some sections (especially the Results and Discussion).
- Discussion: This should emphasize the present findings and their differences or similarities with other work done in the field by other workers.
- Conclusion: Emphasize the new and important aspects of the study in the conclusion.

 
• Review Articles (Narrative Review, Systematic Review, Meta-Analysis)‎

Review articles should contain up to 5000 words (allowed reference count is 85, allowing ‎ illustrations/tables & figures is 7).  The abstract for Review articles should not exceed 250 words.‎ Authors should report systematic reviews in accordance with the PRISMA (Preferred ‎Reporting Items ‎for Systematic Reviews and Meta-Analyses) statement. The body of the Systematic Review and Meta-Analysis should be subdivided into the following ‎sequential sections: ‎Background, Objectives, Materials & Methods (Data Sources, Study Selection, ‎Data ‎Extraction, Statistical analysis, etc.) Results, Discussion, and Conclusions. Abstracts should ‎be ‎structured as: Background, Objectives, Materials & Methods, Results, and Conclusions. Narrative review should be subdivided into the Introduction, Body (divided by headings/subheadings ‎if needed), and conclusion. The abstract for Narrative review should not be structured.‎

• Case Report
Abstract for case report should be prepared in an unstructured format (Maximim 150 words). The body of the case report should be structured as: Introduction, Case presentation, and Discussion.
 
• Brief Report
Reports should contain up to 1500 words with a structured abstract of 200 words maximum subdivided into: Background, Objectives, Materials/Patients and Methods, Results, and conclusion. The body of Brief Report should be structures into Background, Objectives, Materials/Patients and Methods, Results, Discussion and conclusion. Allowed reference count is 20, allowed illustrations/tables & figures is 6.
 
• Letter to Editor
Letters to the editor will be considered if they give significant comments on recent articles published in this journal or they contain relevant preliminary data providing new insights. Letters need no abstract and must cite the previous article in this journal that is being discussed, and should have no more than 10 references and should not exceed 1000 words. Table and Figure are not allowed in letter to editors.
 
• Manuscript Preparation
Manuscripts should be in Word Document (Microsoft Word 97, 2003, 2007, 2010, 2013) in English and should follow the style of the Uniform Requirements for Manuscripts Submitted to Biomedical Journals, a copy of which can be found at www.icmje.org.

• Fonts
Use the font Times New Roman size 12 for the body, size 12 bold for subheadings, headings, and title, Line  spacing = Double.

• Units, Symbols, and Abbreviations
Internationally accepted units (International System of Units), symbols, and abbreviations must be used. Abbreviations should be used sparingly and must be introduced in parentheses upon the first mention.
• Drug Names: Generic drug names must be used.

• Keywords
A list of 3-10 keywords must be provided for original articles, case reports, brief reports and review articles that should be placed after the abstract.
All keywords should be provided according to MeSH terms at:
http://www.nlm.nih.gov/mesh/MBrowser.html.

• Tables
All tables must be included at the end of the manuscript (each table on a separate page).

• Figures
Figures must be included at the end of the manuscript (each figure on a separate page).The figure caption should be attached below the figure. In figures with subparts, the identifier should be placed at the left upper corner of each subpart, using capital letters entailed in parenthesis. Resolution should be 300 dpi for a 3*2 inch figure.
 
• References
This journal accepts references according to Vancouver style (with some minor changes) rules established by the International Committee of Medical journal Editors. In the Vancouver system, the only indication required in the text of a paper is a number, allocated in ascending sequence, and presented in the text either in brackets, or in superscript. For example:“Recent randomized controlled trials in primary care showed benefits for patients with depression from increased telephone support, better cooperation between primary care and mental health professionals, and more systematic follow up (7).”If the same source is cited again later in the text, the same number is used once more. If multiple references are cited, use a hyphen to join an inclusive range of numbers thus: (2-5). Use commas without spaces to separate non-inclusive numbers in a multiple citation thus: (2-5, 7, 10).

• Books and Other Monographs
The details needed to construct a book reference are presented below. Each author’s surname followed by the initials (in the same order as they appear on the title page), a comma should separate each author’s name. Title of the book. Edition of the book if there has been more than one. Place of publication or town of origin followed by a colon, Publisher’s name, followed by a semi-colon, Year of publication. e.g. Ford MJ, Munro JF. Introduction to Clinical Examination. 7th ed. Edinburgh: Churchill Livingstone; 2000. If only a part is cited, add the page numbers, and volume number in the case of multi-volume works, at the end of the reference. Meltzer PS, Kallioniemi A, Trent JM. Chromosome Alterations in Human Solid Tumors. In: Vogelstein B, Kinzler KW, editors. The Genetic Basis of Human Cancer. New York: McGraw-Hill; 2002. p. 93-113. If you need to reference a book written by more than six authors, list the first six authors’ names followed by “et al” thus: Cohen J, Brown A, Smith B, Jones G, Murphy M, McKay P et al.

• Standard Journal Article
List the first six authors followed by et al., paper title, journal title abbreviation, year of publishing, volume number, issue number in parentheses, page range. e. g. Meydani SN, Leka LS, Fine BC, Dallal GE, Keusch GT, Singh MF, et al. Vitamin E and Respiratory Tract Iinfections in Elderly Nursing Home Residents: a Randomized Controlled Trial. JAMA. 2004 Aug 18;292(7):828-36.
* Important note: The abbreviated names of the journal should be used in referencing.

• Online Sources
For all websites references you need to note the date that you accessed the information, and database name or web address (URL). e.g.Royal College of General Practitioners. The Primary Health Care Team. RCGP website 2003 [cited 2004 Sep 22]; Available from: URL: http://www.
rcgp.org.uk/information/publications/information/PDFInfo/21_OCT_03.pdf

• Review Process
All submitted manuscripts are subject to peer review and editorial approval. Articles will be sent to at least 2 reviewers. Authors are usually notified within 1-2 months about the acceptability of their manuscript. Once receiving reviewers comments, authors are requested to send the revised article, and a copy of their reply to the reviewers, including the comment
and explaining the replies to questions and changes made to the revised version within 72 hours.

• Proofs
Proofs will be sent to the corresponding author. Galley proofs should be returned within 72 hours from receipt.
 
• License
This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.