AU - Hassani, Mohammad AU - Shariyate, Mohammad Javad AU - Taraz Jamshidi, Shirin AU - Hallaj Moghaddam, Mohammad Hallaj Moghaddam AU - Omidi-Kashani, Farzad TI - Vanishing Bone Syndrome; A Diagnosis Dilemma: Report of a Rare Case and Literature Review PT - JOURNAL ARTICLE TA - iums-jros JN - iums-jros VO - 6 VI - 1 IP - 1 4099 - http://jros.iums.ac.ir/article-1-251-en.html 4100 - http://jros.iums.ac.ir/article-1-251-en.pdf SO - iums-jros 1 ABĀ  - Gorham-Stout syndrome is a rare disease, which results in spontaneous bone resorption. Failure to proper diagnosis of this syndrome can lead to unnecessary bone surgeries. A 13 years old girl with right hip pain, limping, and proximal femur lytic lesions underwent three surgeries without the exact diagnosis. Surgical curettage, bone graft, and internal fixation failed miserably. According to the imaging studies and the biopsy results of bone lesions that showed lymphangiomatosis, accompanied by skin and spleen lesions, a rare presentation of the Gorham-Stout syndrome was diagnosed. Bisphosphonate treatment provides a significant recovery in her symptoms and imaging studies confirmed bone improvement. CP - IRAN IN - Mashhad University of Medical Sciences, Mashhad, Iran LG - eng PB - iums-jros PG - 0 PT - YR - 2019