en جراحی زانو Knee surgery مروری Review Paper <div style="text-align: justify;">Total joint arthroplasty (TJA) of the lower extremities is a successful surgical procedure for end-stage degeneration and is gaining increasing popularity worldwide. Preexisting neurological conditions have been a significant challenge for arthroplasty surgeons for a long time, and they have avoided performing TJA in these patients. Parkinson&rsquo;s disease (PD), an age-related neurodegenerative disorder, is prevalent and associated with a higher likelihood of gait imbalance, falling, and osteoarthritis (OA). The number of patients with PD who experience hip and knee OA is increasing. As a result, some of these individuals may need to undergo total hip or knee arthroplasty (THA/TKA) to alleviate symptoms and improve their function. Patients with PD present a remarkable set of challenges for surgeons owing to increased muscle tone, higher fracture risk, and ligament instability. Currently, limited information is available regarding the outcomes and effectiveness of these procedures in PD patients. The lack of data is a concern because it prevents surgeons from making informed decisions regarding the use of TJA in this patient population. This study aims to summarize the recent literature regarding total hip arthroplasty (THA) and total knee arthroplasty (TKA) procedures in patients with PD to help surgeons in this challenging setting and improve their knowledge of potential complications and outcomes in this complex background.</div> Arthroplasty, Parkinson’s disease (PD), Surgery, Hip, Knee 201 216 http://jros.iums.ac.ir/browse.php?a_code=A-10-1606-1&slc_lang=en&sid=1 Alireza Ghanbari Alireza.ghanbari92@yahoo.com 10031947532846007633 10031947532846007633 No Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Hooman Yahyazadeh yahyazadehhooman@yahoo.com 10031947532846007634 10031947532846007634 No Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Abolfazl Bagherifard bagherifard.a@iums.ac.ir 10031947532846007635 10031947532846007635 No Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Karo Khosravi karo.kh07@yahoo.com 10031947532846007636 10031947532846007636 No Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Amir Azimi Fanoodi.af@gmail.com 10031947532846007637 10031947532846007637 No Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Reza Ahmadi Reza3732@gmail.com 10031947532846007638 10031947532846007638 No Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Tahereh Farkhondeh farkhondeh2324@gmail.com 10031947532846007639 10031947532846007639 No Department of Toxicology and Pharmacology, School of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran. Babak Roshanravan babak.137595@yahoo.com 10031947532846007640 10031947532846007640 Yes Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Saeed Samarghandian samarghandians1@nums.ac.ir 10031947532846007641 10031947532846007641 No Department of Medical Physiology, School of Medicine, Neyshabur University of Medical Sciences, Neyshabur, Iran.