<?xml version="1.0" encoding="utf-8"?>
<journal>
<title>Journal of Research in Orthopedic Science</title>
<title_fa>Journal of Research in Orthopedic Science</title_fa>
<short_title>JROS</short_title>
<subject>Medical Sciences</subject>
<web_url>http://jros.iums.ac.ir</web_url>
<journal_hbi_system_id>1</journal_hbi_system_id>
<journal_hbi_system_user>admin</journal_hbi_system_user>
<journal_id_issn>2676-7031</journal_id_issn>
<journal_id_issn_online>2676-7031</journal_id_issn_online>
<journal_id_pii>8</journal_id_pii>
<journal_id_doi>10.32598/JROSJ</journal_id_doi>
<journal_id_iranmedex></journal_id_iranmedex>
<journal_id_magiran></journal_id_magiran>
<journal_id_sid></journal_id_sid>
<journal_id_nlai>8888</journal_id_nlai>
<journal_id_science></journal_id_science>
<language>en</language>
<pubdate>
	<type>jalali</type>
	<year>1403</year>
	<month>8</month>
	<day>1</day>
</pubdate>
<pubdate>
	<type>gregorian</type>
	<year>2024</year>
	<month>11</month>
	<day>1</day>
</pubdate>
<volume>11</volume>
<number>4</number>
<publish_type>online</publish_type>
<publish_edition>1</publish_edition>
<article_type>fulltext</article_type>
<articleset>
	<article>


	<language>en</language>
	<article_id_doi></article_id_doi>
	<title_fa></title_fa>
	<title>Pediatric Tumor Resection and Recon-struction: Outcomes of Osteoarticular Allograft Fix-ation With Stabilized Dynamized Nailing Technique</title>
	<subject_fa>تومور</subject_fa>
	<subject>Tumor surgery</subject>
	<content_type_fa>پژوهشی</content_type_fa>
	<content_type>Research Article</content_type>
	<abstract_fa></abstract_fa>
	<abstract>&lt;strong&gt;Background&lt;/strong&gt;: Reconstructing large bone defects after lower limb tumor resection remains a challenge in pediatric orthopedics. While osteoarticular allografts offer a biological solution, achieving stable fixation and union is crucial to minimize complications such as fractures and nonunions.&amp;nbsp;&lt;br&gt;
&lt;strong&gt;Objectives&lt;/strong&gt;: We aimed to explore a novel, stabilized, dynamized nailing technique (SDNT) to enhance outcomes in pediatric patients undergoing tumor resection and reconstruction.&lt;br&gt;
&lt;strong&gt;Methods&lt;/strong&gt;: Between 2014 and 2024, 40 pediatric patients (Mean&amp;plusmn;SD age: 11.85&amp;plusmn;2.93 years) with malignant bone tumors (70.73% osteosarcoma, 24.39% Ewing sarcoma, 2.44% chondrosarcoma) underwent wide resection (&amp;ge;2 cm margins) and reconstruction with fresh frozen osteoarticular allografts (FFOA) soaked in gentamicin. Fixation was achieved using SDNT, a modified intramedullary nailing (IMN) approach designed to promote union through controlled dynamization. Patients were followed for a Mean&amp;plusmn;SD of 33.68&amp;plusmn;20.58 months, with outcomes including union time, complications, and survival assessed via clinical and radiographic evaluations.&lt;br&gt;
&lt;strong&gt;Results&lt;/strong&gt;: The Mean&amp;plusmn;SD union time was 9.71&amp;plusmn;3.05 months. Complications occurred in 48.88% of patients, with delayed union (24.39%), infection (14.64%), and drop foot (4.88%) being the most common. Notably, no fractures occurred except for nail bending (2.44%). Survival was 70.73%, with a 29.27% mortality rate and 17.07% disease relapse. Metastasis affected 29.27% of patients, primarily in the lungs (26.83%).&lt;br&gt;
&lt;strong&gt;Conclusion&lt;/strong&gt;: SDNT with osteoarticular allografts offers a promising approach for pediatric lower limb tumor reconstruction, achieving a low fracture rate and effective bone union despite a high overall complication rate. These findings suggest SDNT may improve mechanical stability compared to traditional fixation methods, warranting further investigation.</abstract>
	<keyword_fa></keyword_fa>
	<keyword>Pediatric bone tumors, Osteoarticular allograft, Stabilized dynamized nailing, Intramedullary nailing (IMN), Lower limb reconstruction, Tumor resection, Osteosarcoma, Ewing sarcoma, Bone :union:, Fresh frozen allograft, Gentamicin-soaked allograft</keyword>
	<start_page>213</start_page>
	<end_page>220</end_page>
	<web_url>http://jros.iums.ac.ir/browse.php?a_code=A-10-1846-2&amp;slc_lang=en&amp;sid=1</web_url>


<author_list>
	<author>
	<first_name>Sam Aliliu</first_name>
	<middle_name></middle_name>
	<last_name>Sami</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>samhaji@yahoo.com</email>
	<code>10031947532846008351</code>
	<orcid>10031947532846008351</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Khalil</first_name>
	<middle_name></middle_name>
	<last_name>Kargar</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>khalilkargar63@gmail.com</email>
	<code>10031947532846008352</code>
	<orcid>10031947532846008352</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Roshanak</first_name>
	<middle_name></middle_name>
	<last_name>Shams</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>shams.rosha.86@gmail.com</email>
	<code>10031947532846008353</code>
	<orcid>10031947532846008353</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Bushra</first_name>
	<middle_name></middle_name>
	<last_name>Zareie</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>shafabushra@gmail.com</email>
	<code>10031947532846008354</code>
	<orcid>10031947532846008354</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>shahabaldin</first_name>
	<middle_name></middle_name>
	<last_name>Beheshti Fard</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>shahab.dr71@gmail.com</email>
	<code>10031947532846008356</code>
	<orcid>10031947532846008356</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Bone and Joint Reconstruction Research Center, Department of Orthopedics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Amin</first_name>
	<middle_name></middle_name>
	<last_name>Hamidzadehkhiavi</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>drahkh2000@gmail.com</email>
	<code>10031947532846008355</code>
	<orcid>10031947532846008355</orcid>
	<coreauthor>Yes
</coreauthor>
	<affiliation>Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


</author_list>


	</article>
</articleset>
</journal>
