en شانه / آرنج Shoulder / Elbow مروری Review Paper <div style="text-align: justify;">Postarthroscopic glenohumeral chondrolysis (PAGCL) is a rare but catastrophic complication following shoulder arthroscopy, characterized by rapid and irreversible degeneration of articular cartilage, leading to persistent pain, stiffness, and severe functional impairment. Although its incidence is low, PAGCL predominantly affects young and active patients and often results in early joint failure requiring surgical intervention. The condition has been increasingly associated with potentially modifiable iatrogenic factors, particularly the intra-articular use of local anesthetics. Due to its devastating consequences and lack of standardized management guidelines, early recognition and prevention are of paramount importance. This mini-review summarized the current evidence regarding the epidemiology, proposed pathophysiological mechanisms, clinical presentation, diagnostic considerations, and available treatment strategies for PAGCL, with an emphasis on prevention and clinical decision-making.</div> Postarthroscopic glenohumeral chondrolysis (PAGCL), Shoulder arthroscopy, Cartilage toxicity, Local anesthetics, Prevention 117 120 http://jros.iums.ac.ir/browse.php?a_code=A-10-2734-1&slc_lang=en&sid=1 Morteza Nakhaei Amroodi drmna@yahoo.com 10031947532846008650 10031947532846008650 No Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Pouria Tabrizian tabrizian.pouria@gmail.com 10031947532846008651 10031947532846008651 No Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Babak Hashemipour drbabakhashemi@gmail.com 10031947532846008652 10031947532846008652 Yes Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Mohammad Mahdi Mahdavifar mahdavifarmohammadmehdi@gmail.com 10031947532846008653 10031947532846008653 No Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Mojtaba Baniasadi mojtaba.baniasadi20@gmail.com 10031947532846008654 10031947532846008654 No Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Mohammadreza Bahaeddini mrbahaeddini@yahoo.com 10031947532846008655 10031947532846008655 No Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Mojtaba Khajeh Alizadeh Attar mojtaba.attar75@gmail.com 10031947532846008656 10031947532846008656 No Department of Orthopedics, Bone and Joint Reconstruction Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.