Volume 7, Issue 1 (2-2020)                   J. Res. Orthop. Sci. 2020, 7(1): 41-46 | Back to browse issues page


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Nakhaee Amroodi M, Bagherifard A, Jabalameli M, Salehpour M, Majdi S. Alkaptonuric Ochronosis Superimposed With Septic Arthritis in a Middle-aged Man. J. Res. Orthop. Sci.. 2020; 7 (1) :41-46
URL: http://jros.iums.ac.ir/article-1-2055-en.html
1- Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences,Tehran, Iran.
Abstract:   (147 Views)
Alkaptonuria is a rare inborn metabolic disease, in which an enzymatic deficiency accumulates alkapton in different tissues, causing darkness and injury, especially in spine and large cartilages, called ochronosis. The urine darkness can be a key to early diagnosis in childhood, but some cases are missed until adulthood and gradual damage to cartilages causes disability and impairs the patients’ quality of life. Here, a 49-year old male patient is presented with a 2 week history of left knee pain and swelling, who underwent arthrotomy, and the macro- and microscopic evaluation revealed ochronosis, superimposed by septic arthritis. Diagnosis of this rare disease should be considered in differential diagnoses of common joint disorders, like septic arthritis and osteoarthritis, so that appropriate management of the disease can prevent further damages.
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Type of Study: Research Article | Subject: General
Received: 2019/07/5 | Accepted: 2019/12/10 | Published: 2020/02/1

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