Volume 10, Issue 3 (8-2023)
JROS 2023, 10(3): 135-144 |
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Bahaeddini M R, Jafari B, Rikhtehgar M, Aminian A, Tabrizian P, Mirjalily M S, et al . Correlation Between Bone Density Measured by Routine BMD and Hounsfield Units Assessed on Diagnostic CT-scan: A Cross-sectional Study. JROS 2023; 10 (3) :135-144
URL: http://jros.iums.ac.ir/article-1-2254-en.html
URL: http://jros.iums.ac.ir/article-1-2254-en.html
Mohammad Reza Bahaeddini1 
, Behnam Jafari1 , Masih Rikhtehgar1 , Amir Aminian1 , Pouria Tabrizian1 , Mohammad Sadegh Mirjalily1 , Shayan Amiri1 , Javad Khaje Mozafari1 , Hamed Tayyebi 1
, Behnam Jafari1 , Masih Rikhtehgar1 , Amir Aminian1 , Pouria Tabrizian1 , Mohammad Sadegh Mirjalily1 , Shayan Amiri1 , Javad Khaje Mozafari1 , Hamed Tayyebi 1
1- Department of Orthopedics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Abstract: (178 Views)
Background: Previous studies have shown a moderate correlation between bone mineral density (BMD) measured by dual-energy x-ray absorptiometry (DEXA) and Hounsfield units (HU) assessed on diagnostic computed tomography (CT) scans in the lumbar spine.
Objectives: In this study, we aimed to evaluate the correlation between DEXA scores and HU values for different bones and several anatomical landmarks.
Methods: In this retrospective study, 214 patients underwent DEXA and diagnostic CT scans of different bones, including the proximal humerus (n=96), distal tibia (n=56), distal femur (n=34), and proximal tibia (n=28). HU values of five anatomic landmarks, including the medulla, anteromedial cortex, anterolateral cortex, posteromedial cortex, and posterolateral cortex, were measured, and their correlation with the lowest T-score of the patients was assessed.
Results: The HU of the center of the medulla was significantly correlated with the lowest T-score in the proximal (r=0.486, P=0.04) and distal tibia (r=0.458, P=0.01). In the proximal humerus, the HU of the anteromedial cortex was significantly correlated with the lowest T-score (r=0.0353, P=0.01). The mean HU of the posterolateral cortex in the proximal humerus was significantly smaller in the osteoporotic patients (P=0.003). The mean HU of the center of the medulla in the proximal tibia was significantly lower in patients with osteoporotic (P=0.036). The mean HU values of the posteromedial cortex and center of the medulla in the distal tibia were significantly larger in patients with normal BMD (P=0.04 both).
Conclusion: A moderately significant correlation is observed between the lowest T-score and specific anatomical landmarks of the different bones.
Objectives: In this study, we aimed to evaluate the correlation between DEXA scores and HU values for different bones and several anatomical landmarks.
Methods: In this retrospective study, 214 patients underwent DEXA and diagnostic CT scans of different bones, including the proximal humerus (n=96), distal tibia (n=56), distal femur (n=34), and proximal tibia (n=28). HU values of five anatomic landmarks, including the medulla, anteromedial cortex, anterolateral cortex, posteromedial cortex, and posterolateral cortex, were measured, and their correlation with the lowest T-score of the patients was assessed.
Results: The HU of the center of the medulla was significantly correlated with the lowest T-score in the proximal (r=0.486, P=0.04) and distal tibia (r=0.458, P=0.01). In the proximal humerus, the HU of the anteromedial cortex was significantly correlated with the lowest T-score (r=0.0353, P=0.01). The mean HU of the posterolateral cortex in the proximal humerus was significantly smaller in the osteoporotic patients (P=0.003). The mean HU of the center of the medulla in the proximal tibia was significantly lower in patients with osteoporotic (P=0.036). The mean HU values of the posteromedial cortex and center of the medulla in the distal tibia were significantly larger in patients with normal BMD (P=0.04 both).
Conclusion: A moderately significant correlation is observed between the lowest T-score and specific anatomical landmarks of the different bones.
Keywords: Dual-energy x-ray absorptiometry, Bone mineral density (BMD), Hounsfield unit (HU), Computed tomography scan (CT)
Type of Study: Research Article |
Subject:
Trauma
Received: 2023/02/21 | Accepted: 2023/06/9 | Published: 2023/08/1
Received: 2023/02/21 | Accepted: 2023/06/9 | Published: 2023/08/1
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