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Nakhaei Amroodi M, Roshanravan B, Bahaeddini M, Sobhani A, Baniasadi M, Amiri S et al . Edwardsiella tarda in a Young-aged Woman Without Underlying Diseases: A Case Report and Review of the Literature. JROS 2024; 11 (3) :173-176
URL: http://jros.iums.ac.ir/article-1-2279-en.html

Background: Edwardsiella tarda (a gram-negative bacterium) is an unusual human pathogen that is commonly isolated from aquatic animals like fish. Gastrointestinal symptoms are the most common manifestations of this bacterium; meanwhile, extraintestinal infections can also occur in humans, especially in people with immunodeficiency diseases.
Case Presentation:  A 25-year-old Iranian woman who presented with a fracture of the greater tuberosity of the humerus underwent surgery with a deltopectoral approach with ETHIBOND EXCEL™ suture. She presented with pain, limited mobility, and fever 3 months after the surgery. A tissue culture sample was obtained, which was reported to be E. tarda. The patient showed uneventful recovery after antibiotic therapy with ciprofloxacin 500 mg, twice a day, as well as clindamycin 300 mg, thrice a day.
Conclusion: Although extraintestinal and systemic infections of E. tarda usually occur in patients with an underlying disease such as immunodeficiency or malignancy, we suggest that E. tarda infection might show extraintestinal manifestations even in patients without any known underlying diseases.