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Nakhaei Amroodi M, Tabrizian P, Hashemipour B, Mahdavifar M M, Baniasadi M, Bahaeddini M et al . Postarthroscopic Glenohumeral Chondrolysis: A Clinical Review. JROS 2025; 12 (3) :117-120
URL: http://jros.iums.ac.ir/article-1-2301-en.html

Postarthroscopic glenohumeral chondrolysis (PAGCL) is a rare but catastrophic complication following shoulder arthroscopy, characterized by rapid and irreversible degeneration of articular cartilage, leading to persistent pain, stiffness, and severe functional impairment. Although its incidence is low, PAGCL predominantly affects young and active patients and often results in early joint failure requiring surgical intervention. The condition has been increasingly associated with potentially modifiable iatrogenic factors, particularly the intra-articular use of local anesthetics. Due to its devastating consequences and lack of standardized management guidelines, early recognition and prevention are of paramount importance. This mini-review summarized the current evidence regarding the epidemiology, proposed pathophysiological mechanisms, clinical presentation, diagnostic considerations, and available treatment strategies for PAGCL, with an emphasis on prevention and clinical decision-making.